Is Cialis a promising option to treat Muscular Dystrophy?

Patients suffering from muscle atrophy undergo inadequate blood flow to the muscles which leads to fatigue and decreased performance. This leads to muscle weakness from infancy leading to deformities in the spine and the limbs and almost no functioning by the time one reaches teenage. Scientists have been researching to find ways to restore the blood management of an effective body to benefit muscle strength and operation. Recent pharmaceutical research has propounded Cialis to be one of the most effective ways to treat muscular dystrophy. Although it is not being hailed as the one true cure but it has been successful in providing immediate and complete symptomatic relief. This has caused the research bells to ring for doctors who are finding themselves with a floodgate of probable cures.

How Cialis work in treating Muscular dystrophy?

Cialis though prescribed for pulmonary hypertension and erectile dysfunction has been proven to work for patients suffering from muscle dystrophy. The principle of operation remains the same. The drug allows blood to flow smoothly to the oxygen-starved muscles consequently providing immediate relief. However, it is not known if the drug could sustain the management of blood flow with its long-term use. Moreover, it is still not clear if the drug can manage to slow down the progression of a disease and preserve the muscle mass.

What is the science behind Cialis in treating Muscular Dystrophy?

Putting it very simply, the body’s nerve cells produces Nitrogen oxide which facilitates the creation of an enzyme called cGMP. The cGMP is responsible for dilating the blood vessels leading to an increase in the blood flow. However, another enzyme called the PDE-5 is responsible for destroying the cGMP. Cialis does nothing more than stopping the PDE-5 from breaking down the cGMP. This allows more blood to flow in the vessels and provide more oxygen to the muscles, chemically.

How promising are the results of Cialis usage in muscular dystrophy treatment?

The drug’s effect was dramatic and immediate when conducted on mice which have the same mutations as humans in this regard. Seeing its effectiveness, the researchers conducted the study on boys suffering from muscle dystrophy. It was found that even a single dose of Cialis was capable of restoring the blood flow to the muscle. The results were found to be more profound with higher dosage. The only side effect was an increase in erections of the boys which has been disregarded as a harmless by-standing symptom for now. This has led to some conjecture on Cialis’ efficacy as a long-term therapeutic treatment for which clinical trials have already been initiated. The present treatment involves cardiac-protective blood pressure drugs and steroids, however, the most they are able to do is delay the side effects of muscle dystrophy for a few years. If Cialis is found to be a successful source in the ongoing clinical trials, it may just transform into a clinical practice. Cialis is a studied and tolerated drug available in online pharmacy with little to none side effects. If the ongoing research is successful, it would be an incredible breakthrough for treating muscle dystrophy.